Graduated from Athens Medical School in 1983 and completed internal medicine training in 1990. In 1995 awarded PhD from the University of London on monoclonal antibodies in Head and Neck Cancer. He was appointed at the University of Hull in 1999 as part of the founding team of Hull York Medical School, where he is now professor of Cancer Medicine.
His laboratory interests include the molecular role of tissue Factor (TF) in the propagation of cancer. Amongst his clinical research activity he has been national chief investigator for a number of studies in cancer associated thrombosis. He has published widely in this field with particular focus on the thromboprophylaxis of the ambulant cancer patient and the management of incidental pulmonary embolism in cancer patients. He treats pancreaticobiliary, kidney cancer and melanoma.